Description
Product Characteristics:
Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG2. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization.
Subcellular location: Cytoplasm
Synonyms: PAC1, DSCR2, PAC-1, C21LRP, LRPC21, Proteasome assembly chaperone 1, Chromosome 21 leucine-rich protein, C21-LRP, Down syndrome critical region protein 2, PSMG1
Target Information: Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with psmg2 (By similarity)